Abstract: Vanadium and chromium have the similar chemical properties and naturally coexist at most occasions,so the problem for separation of vanadium and chromium has not been properly solved for a long time.The solvent extraction is currently the most common method for the separation of vanadium and chromium. Traditional extraction systems for vanadium-chromium separation,including neutral complexation extraction system,ion association extraction system,acidic complexation and chelation extraction system,synergistic extraction system,were introduced.Three-liquid phase extraction system was used as an example for introducing a novel extraction system. Furthermore,the advantages and disadvantages of each extraction system were analyzed. Three-liquid phase extraction system is expected to have a broad prospect due to a high separation factor,well physical phenomena,short process flow,simple operation,low cost and flexible ratio of extractant,considering the environment protection and company benefits.