稀土对HA/Ti复合材料力学及生物活性影响的研究

范兴平; 杨成

doi:10.7513/j.issn.1004-7638.2023.06.011

稀土对HA/Ti复合材料力学及生物活性影响的研究

doi: 10.7513/j.issn.1004-7638.2023.06.011

范兴平,
杨成

攀枝花学院钒钛学院, 四川攀枝花617000

基金项目: 四川省科技计划项目（项目编号：2022YFSY0044）。

详细信息

作者简介:
范兴平，1979年出生，男，四川广安人，博士，教授，主要从事钒钛新材料研究，E-mail：fanxingping123@163.com

中图分类号: TF823,TG135.5
计量
- 文章访问数: 49
- HTML全文浏览量: 14
- PDF下载量: 2
- 被引次数: 0
出版历程
- 收稿日期: 2023-03-21
- 网络出版日期: 2024-01-11
- 刊出日期: 2023-12-30

Study on effect of rare earths on the mechanical and biological activity of HA/Ti composites

School of Vanadium and Titanium, Panzhihua University, Panzhihua 617000, Sichuan, China

摘要

摘要: 为进一步改善HA/Ti复合材料的性能，以HA粉及商用Ti粉为原料，分别加入一定量的不同稀土化合物（CeO₂、LaF₃及SrO），利用粉末冶金方法制备了稀土增强型HA/Ti生物复合材料。借助X射线衍射仪（XRD）、扫描电镜（SEM）、金相显微镜及万能力学试验机，探究了三种稀土元素对HA/Ti复合材料组织结构、力学性能及生物活性的影响。结果表明，分别添加0.3%的CeO₂、LaF₃及SrO稀土化合物所得的三种复合材料的力学性能均得以改善，其抗压强度分别为47、91 MPa和40 MPa，而未添加稀土的HA/Ti复合材料的抗压强度仅为34 MPa；且LaF₃还能进一步改善复合材料的生物活性，但添加CeO₂和SrO未能改善其生物活性。
- HA/Ti复合材料 /
- 粉末冶金 /
- 稀土 /
- 抗压强度 /
- 生物活性
Abstract: In order to further improve the properties of HA/Ti composite materials, using HA powder and commercial Ti powder as raw materials, adding a certain amount of different rare earth complexes (CeO_2, LaF₃ and SrO), a rare earth reinforced HA/Ti biological composite material was prepared by powder metallurgy method. The effects of three rare earth elements on the microstructure, mechanical properties, and biological activity of HA/Ti composites were investigated using X-ray diffraction (XRD), scanning electron microscopy (SEM), metallographic microscopy and universal mechanical testing machines. The results show that the mechanical properties of the three composites obtained by adding 0.3% CeO₂, LaF₃, and SrO rare earth compounds are improved, with compressive strengths of 47, 91 MPa, and 40 MPa, respectively, while the compressive strength of the HA/Ti composite without adding rare earth compounds is only 34 MPa. Moreover, LaF₃ can further improve the biological activity of the composite material, but adding CeO₂ and SrO cannot improve its biological activity.
- HA/Ti compound material /
- powder metallurgy /
- rare earth /
- compressive strength /
- biological activity

HTML全文

图 1 HA/Ti添加不同稀土的金相组织

Figure 1. Metallographic diagrams of HA/Ti with different rare earth elements

(a)HA/Ti; (b)HA/Ti+0.3%CeO₂; (c)HA/Ti+0.3%LaF₃; (d) HA/Ti+0.3%SrO

下载: 全尺寸图片幻灯片

图 2 添加稀土前后复合材料的XRD谱

(a)为HA/Ti试样；(b)、(c)和(d)分别为添加CeO₂、LaF₃及SrO后的试样

Figure 2. XRD spectra of composites before and after adding rare earths

下载: 全尺寸图片幻灯片

图 3 稀土对复合材料抗压强度的影响

Figure 3. Effect of rare earths on compressive strength of composite materials

下载: 全尺寸图片幻灯片

图 4 不同稀土增强复合材料在SBF溶液中浸泡7天后形貌的SEM图像

Figure 4. SEM images of morphology of different rare earth reinforced composites after immersion in SBF solution for 7 days

(a)HA/Ti; (b)HA/Ti+0.3%CeO₂; (c)HA/Ti+0.3%LaF₃; (d)HA/Ti+0.3%SrO

下载: 全尺寸图片幻灯片

图 5 加入LaF₃后的复合材料在SBF溶液中浸泡7天后的XRD谱

Figure 5. XRD pattern of composite material after adding LaF₃ and soaking in SBF solution for 7 days

下载: 全尺寸图片幻灯片

参考文献(16)

[1]	Hazwani M R, Lim L X, Lockman Z, et al. Fabrication of titanium-based alloys with bioactive surface oxide layer as biomedical implants: Opportunity and challenges[J]. Transactions of Nonferrous Metals Society of China, 2022,32:1−44. doi: 10.1016/S1003-6326(21)65776-X
[2]	Li F, Jiang X S, Shao Z Y, et al. Microstructure and mechanical properties of nano-carbon reinforced titanium matrix/hydroxyapatite biocomposites prepared by spark plasma sintering[J]. Nanomaterials, 2019,8(9):729.
[3]	Hindy A, Farahmand F, Tabatabaei F S. In vitro biological outcome of laser application for modification or processing of titanium dental implants[J]. Lasers in Medical Science, 2017, 32(5): 1197-1206.
[4]	Giner L, Mercadé M, Torrent S, et al. Double acid etching treatment of dental implants for enhanced biological properties[J]. Journal of Applied Biomaterials & Functional Materials, 2018,16(2):83−89.
[5]	Xia L, Xie Y, Fang B, et al. In situ modulation of crystallinity and nano-structures to enhance the stability and osseointegration of hydroxyapatite coatings on Ti-6Al-4V implants[J]. Chemical Engineering Journal, 2018,347:711−720. doi: 10.1016/j.cej.2018.04.045
[6]	Harjit S, Sunpreet S, Chander P, et al. Experimental investigation and parametric optimization of HA-TiO₂ plasma spray coating on β-phase titanium alloy[J]. Materials Today:Proceedings, 2020,3(28):1340−1344.
[7]	Xie F X, Huang J B, Yang H, et al. Ti-10Mo/hydroxyapatite composites for orthopedic applications: Microstructure, mechanical properties and biological activity[J]. Materials Today Communications, 2021,29:102887. doi: 10.1016/j.mtcomm.2021.102887
[8]	Arifin A, Sulong A B, Muhamad N, et al. Material processing of hydroxyapatite and titanium alloy(HA/Ti) composite as implant materials using powder metallurgy: A review[J]. Materials & Design, 2014,55(6):165−175.
[9]	Egorov A, Smirnov V, Shvorneva L, et al. High-temperature hydroxyapatite-titanium interaction[J]. Inorganic Materials, 2010,46:168−171. doi: 10.1134/S0020168510020147
[10]	Zhang Guojun, Sun Yuanjun, Niu Rongmei, et al. The strengthening mechanism of rare earth lanthanum oxide doped molybdenum alloys[J]. Rare Metal Materials and Engineering, 2005,34(12):1926−1930. (张国君, 孙院军, 牛荣梅, 等. 稀土氧化镧掺杂钼合金的强化机制研究[J]. 稀有金属材料与工程, 2005,34(12):1926−1930. doi: 10.3321/j.issn:1002-185X.2005.12.020 Zhang Guojun, Sun Yuanjun, Niu Rongmei, et al. The strengthening mechanism of rare earth lanthanum oxide doped molybdenum alloys[J]. Rare Metal Materials and Engineering, 2005, 34(12): 1926-1930. doi: 10.3321/j.issn:1002-185X.2005.12.020
[11]	Wang Bin, Liu Yong, Liu Yanbin, et al. Effects of LaH₂ and LaB₆ addition of microstructure and mechanical property of powder metallurgy Ti alloy[J]. Materials Science and Engineering of Powder Metallurgy, 2011,16(1):136−142. (王斌, 刘咏, 刘延斌, 等. 稀土La对粉末冶金钛合金组织和力学性能的影响[J]. 粉末冶金材料科学与工程, 2011,16(1):136−142. doi: 10.3969/j.issn.1673-0224.2011.01.023 Wang Bin, Liu Yong, Liu Yanbin, et al. Effects of LaH₂ and LaB₆ addition of microstructure and mechanical property of powder metallurgy Ti alloy[J]. Materials Science and Engineering of Powder Metallurgy, 2011, 16(1): 136-142. doi: 10.3969/j.issn.1673-0224.2011.01.023
[12]	Tang Xia, Meng Yukun. Effect of different La contents in hydroxyapatite-coated Ti plate on cytocompatibility of attached cells[J]. Acta Academiae Medicinae Militaris Tertiae, 2011,33(24):2592−2595. (唐霞, 孟玉坤. 钛表面羟基磷灰石涂层含镧量对附着细胞生物学性能的影响[J]. 第三军医大学学报, 2011,33(24):2592−2595. doi: 10.16016/j.1000-5404.2011.24.031 Tang Xia, Meng Yukun. Effect of different La contents in hydroxyapatite-coated Ti plate on cytocompatibility of attached cells[J]. Acta Academiae Medicinae Militaris Tertiae, 2011, 33(24): 2592-2595. doi: 10.16016/j.1000-5404.2011.24.031
[13]	Shao Zhenyi, Li Feng, Zhang Jianlin, et al. Research progress of various nano-materials reinforced and rare earth element doped Ti-HA composited[J]. Metallic Functional Materials, 2017,24(2):13−22. (邵甑胰, 李峰, 张建林, 等. 稀土掺杂纳米相增强Ti-HA复合材料研究进展[J]. 金属功能材料, 2017,24(2):13−22. doi: 10.13228/j.boyuan.issn1005-8192.2016075 Shao Zhenyi, Li Feng, Zhang Jianlin, et al. Research progress of various nano-materials reinforced and rare earth element doped Ti-HA composited[J]. Metallic Functional Materials, 2017, 24(2): 13-22. doi: 10.13228/j.boyuan.issn1005-8192.2016075
[14]	吕凝磊. 掺锶生物玻璃及其与羟基磷灰石复合材料的制备及溶解性研究[D]. 长沙: 中南大学, 2014. Lü Ninglei. Fabrication of Sr-containing bioglass/HA composite and its solubility[D]. Changsha: Central South University, 2014.
[15]	Kokubo T, Takadama H. How useful is SBF in prediction in vivo bone bioactivity[J]. Biomaterials, 2006,27:2907−2915. doi: 10.1016/j.biomaterials.2006.01.017
[16]	Ning Congqin, Zhou Yu, Huang Congchun, et al. In vivo bioactivity of Ti/HA biocomposited by powder metallurgy methods[J]. Journal of Inorganic Materials, 2003,18(4):879−884. (宁聪琴, 周玉, 黄丛春, 等. 粉末冶金法制备Ti/HA生物复合材料的体内生物活性[J]. 无机材料学报, 2003,18(4):879−884. Ning Congqing, Zhou Yu, Huang Congchun, et al. In vivo bioactivity of Ti/HA biocomposited by powder metallurgy methods[J]. Journal of Inorganic Materials, 2003, 18(4): 879-884.