In order to explore the relationship between refining slag,molten steel and inclusion,the activity of components in CaO-MgO-Al2O3-SiO2 refining slag is calculated by Factsage software.The results indicate that aAl2O3,aCaO,aMgO,aSiO2 at 1 600℃ ranges from 0.003 to 0.04,from 0.35 to 0.9,from 0.49 to 0. 9,from 0.000 08 to 0.000 5,respectively,when wMgOis 5%.With the MgO content increasing to 7%,liquid phase zones of refining slag has reduced.In addition,the activity of refining slag has small fluctuation.Furthermore,with the MgO content increasing to 10%,aAl2O3 can be increased by improving the Al2O3 content and decreasing the basicity(R) at the high basicity.On the contrary,aCaO、aMgO and aSiO2 can be increased by improving the basicity and decreasing the content of Al2O3.In addition,the activity of refining slag obtained from hot experiments and thermodynamic simulation are consistent,which indicates that the thermodynamic simulation by Factsage is feasible in predicting the activity of refining slag.