Abstract: In order to study the influence of sand milling process on properties of rutile titanium white,an initial product of rutile titanium dioxide white from the roll-in process was sand milled on a simulated vertical sand mill in laboratory. The results show that the optimum parameters for sand milling process are 30 min of grinding time,2 000 r/min of rotation speed,300 g/L of slurry concentration,65% of filling rate and 1.8 mm of selected zirconium bead size. The stability tests indicate a favorable reproducibility with an average particle size of 236 nm for the slurry after milling. The milling effects by using 1.8 mm zirconium bead are better than that of 0.6 mm industrially adopted zirconium bead. The experimental results can provide important theoretical and technical supports for the improvement of industrial sand milling process.