钛3D打印及其在生物医学植入物中的应用

吴小平; 徐卫; 刘永胜

doi:10.7513/j.issn.1004-7638.2025.06.013

钛3D打印及其在生物医学植入物中的应用

doi: 10.7513/j.issn.1004-7638.2025.06.013

吴小平^{1, 2,},
徐卫³,
刘永胜^{1, 2}

1.
成都先进金属材料产业技术研究院股份有限公司, 四川成都 610301
2.
钒钛资源利用国家重点实验室, 四川攀枝花 617000
3.
萨利大学机械工程系 , Guildford, GU2 7XH, 英国

基金项目: 四川省自然科学基金面上项目（2025ZNSFSC0381）。

详细信息

作者简介:
吴小平，1960年出生，男，四川遂宁人，博士，高级工程师，研究方向为钛化工；E-mail：13308173290@163.com

中图分类号: TF823,TB34
计量
- 文章访问数: 36
- HTML全文浏览量: 16
- PDF下载量: 6
- 被引次数: 0
出版历程
- 收稿日期: 2025-10-13
- 录用日期: 2025-11-19
- 修回日期: 2025-11-14
- 网络出版日期: 2025-12-31
- 刊出日期: 2025-12-31

Titanium 3D printing and its application in biomedical implants

WU Xiaoping^{1, 2
,},
XU Wei³,
LIU Yongsheng^{1, 2}

1.
Chengdu Advanced Metal Materials Industry Technology Research Institute Co., Ltd., Chengdu 610300, Sichuan, China
2.
State Key Laboratory of Vanadium and Titanium Resources Comprehensive Utilization, Panzhihua 617000, Sichuan, China
3.
Department of Mechanical Engineering, University of Surrey, Guildford, GU2 7XH, UK

摘要

摘要: 钛及钛合金具有优越的生物相容性、耐腐蚀性和机械特性，是少数可以安全地植入人体的金属材料，并应用于生物医学，包括植入物、牙科、手术工具、支架、组织工程和体外医疗器械。传统的钛及钛合金生物医学植入物采用减材和成型工艺制造。近年来，随着增材制造（3D打印）技术的发展，生物医学植入物制造可以直接使用来自医学成像获得的数据构建模型，并通过增材制造成型。增材制造生物医学植入物主要应用的技术为激光选区熔化（SLM）、电子束熔化（EBM）和定向能量沉积（DED）。纯钛（CP-Ti）和钛合金（Ti-64）是生物医学应用中最常见的钛金属材料。与传统制造方法相比，增材制造的关键优势是其多维度和个性化制造，且更具可重复性。为了更新钛和钛合金的生物医学植入物研究进展，综述了钛和钛合金、3D打印方法以及钛金属3D打印在生物医学中的应用，讨论和总结了3D打印的钛金属植入物在生物医学中的最新发展，并探讨了钛金属3D打印生物医学植入物的未来研究方向。
- 钛和钛合金 /
- 3D打印 /
- 生物医学植入物
Abstract: Titanium and titanium alloys possess superior biocompatibility, corrosion resistance, and mechanical properties, making them among the few metal materials safe for implantation in the human body. They are widely used in biomedical applications, including implants, dentistry, surgical instruments, stents, tissue engineering, and in vitro medical devices. Biomedical implants made of titanium and titanium alloys are traditionally manufactured through subtractive and forming processes. In recent years, with the advancement of additive manufacturing (3D printing) technology, biomedical implants can now be directly fabricated using data from medical imaging methods, enabling the three-dimensional additive connection of titanium materials to produce components. Selective laser melting (SLM), electron beam melting (EBM), and directed energy deposition (DED) are the primary technologies for the additive manufacturing of titanium components. The most commonly used additive manufacturing titanium materials in biomedical applications are commercially pure titanium (CP-Ti) and titanium alloys (Ti-64). Compared to traditional manufacturing methods, the key advantages of additive manufacturing lie in its multidimensional and personalized production capabilities, along with greater reproducibility. To update the latest advancements in research on titanium and titanium alloy biomedical implants, this paper reviews titanium and titanium alloys, 3D printing methods, and their applications in biomedical implant. It discusses and summarizes the latest developments in 3D-printed titanium implants and explores future research directions for titanium-based 3D-printed biomedical implants.
- titanium and titanium alloys /
- 3D printing /
- biomedical implant

HTML全文

图 1 钛粉末生产系统示意

Figure 1. Illustration of Ti powder production system

(a) EIGA; (b) PA

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图 2 用于 3D 打印的 SLM 系统示意

Figure 2. Illustration diagram of a SLM system for 3D printing

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图 3 EBM技术示意

Figure 3. The schematic diagram of the EBM technique

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图 4 金属增材制造的生物医学应用示意^[79]

Figure 4. Schematic diagram of the biomedical application of additive manufacturing of metals^[79]

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图 5 钛3D 打印牙科植入物^[80]

Figure 5. Titanium 3D printed dental implant^[80]

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图 6 3D打印的颅骨生物模型和仿生患者专用颅骨假体^[89]

（a）~（c）颅骨生物模型；（d）专用颅骨假体

Figure 6. 3D printed skull biomodels and biomimetic patient-specific cranial prostheses^[89]

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图 7 创建个性化脊柱融合器的工作流程

（a）成像; （b）设计; （c）制造^[106]

Figure 7. The workflow for creating personalized surgical plans and implants

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